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Expression of three tet2 isoforms in various cells and tissues.(aTet2 functions in immune regulation. tet2 can regulate the t cell Tet2 (tet methylcytosine dioxygenase 2)Tet2 functions as a resistance factor against dna methylation.
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Tet2 factors downregulate cellular oncotarget figure acquisition infection resistance methylation barr dna
Model showing a simplified diagram proposing the recruitment of tet2Tet2 function frontiersin malignancies regulation hematopoietic immune fonc Tet2 myeloid differentiation functionTet2 binding to enhancers facilitates transcription factor recruitment.
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Schematic diagram of tet2 function in dna repair. tet2 knock-downTet2: a cornerstone in normal and malignant hematopoiesis Negative (blue) or positive (pink) regulation of tet2 in theSpecific functions of tet1 and tet2 in regulating mesenchymal cell.
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| Overview of TET2 structure and functions in different cellular
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Tet2 and Tet3 are upregulated during T cell lineage specification and
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TET2 binding to enhancers facilitates transcription factor recruitment
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Expression of three TET2 isoforms in various cells and tissues.(a
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Sequencing of TET2 gene: a. TET2 variants (c.5060_5061del:p.Q1687fsX3
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Interaction between TET2 and DNA (A) Electrostatic potential surface of
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Specific functions of TET1 and TET2 in regulating mesenchymal cell
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Overview of identified variants within the coding region of TET2